Niche it!
BobbyGs Info

Finish Line

Vasodilators

Drugs & Medication

Vasodilators

Antianginals | PDE5 inhibitors

From Wikipedia the free encyclopedia, by MultiMedia

Back | Home | Up | Next


Vasodilation is where blood vessels in the body become wider following the relaxation of the smooth muscle in the vessel wall. This will reduce blood pressure - since there is more room for the blood. The opposite physiological process is vasoconstriction.

Vasomotor refers to the muscles and nerves controlling the process of vasodilation.

A vasodilator is a substance that causes vasodilation. Several vasodilators are used as drugs which may, for example, allow blood to flow more easily around a clot.

Flushing may be a physiological response to vasodilators.

Natural vasodilators and Drugs that Exploit Them

  • Absence of high levels of environmental noise
  • Adenosine
    • Adenocard - this is primarily used as an anti-arrhythmic.
  • Adrenaline and noradrenaline vasodilate arterioles of the skeletal muscles. (By acting on beta-2 adrenergic receptors.) These chemicals cause vasoconstriction elsewhere.
  • L-Arginine
    Atrial natriuretic peptide (ANP) - a weak vasodilator.
    Bradykinin
    Endothelium-derived hyperpolarizing factor (EDHF)
  • Histamine
    • Complement proteins C3a, C4a and C5a work by triggering histamine release from mast cells and basophil granulocytes.
  • Niacin (aka nicotinic acid)
  • Nitric oxide
    • Glyceryl trinitrate (commonly known as Nitroglycerin)
      Isosorbide mononitrate & Isosorbide dinitrate
      Pentaerythritol Tetranitrate (PETN)
      Sodium nitroprusside
    • PDE5 inhibitors: these agents indirectly increase the effects of nitric oxide
  • Platelet activating factor (PAF)
    Prostacyclin (PGI2) as well as other prostaglandins.
  • Tetrahydrocannabinol (THC) - the major active chemical in marijuana. Its mild vasodilating effects redden the eyes of cannabis smokers.
  • Papaverine an alkaloid found in the opium poppy papaver somniferum

Home | Up | Drug diversion | Drug overdose | Drug resistance | Antipyretics | Bisphosphonates | Dermatological preparations - Sunscreen | Endothelin receptor antagonists | Glycoprotein IIb/IIIa inhibitors | Ointments | Orphan drugs | Patent medicine | Pyrazole | Pyrazolopyrimidines | Drugs in sport | Sympathomimetics | Tocolytics | Triptans | Vasodilators | Erythropoietin (Procrit) | Fluticasone/salmeterol (Advair) | Vasoconstrictor

Drugs & Medication, made by MultiMedia | Free content and software

This guide is licensed under the GNU Free Documentation License. It uses material from the Wikipedia.


Barnes & Noble