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Mescaline

Drugs & Medication

Mescaline

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Mescaline
Chemical name 3,4,5-Trimethoxy-
phenethylamine or
2-(3,4,5-trimethoxyphenyl)
ethanamine
Chemical formula C11H17NO3
Molecular mass 211.26 g/mol
Melting point 128–129 °C
CAS numbers 54-04-6
SMILES NCCC1=CC(OC)=C(OC)C(OC)=C1
Chemical structure of mescaline

Mescaline (3,4,5-trimethoxyphenethylamine) is a hallucinogenic alkaloid of the phenethylamine class.

It occurs naturally in the peyote cactus (Lophophora williamsii), the San Pedro cactus (Echinopsis pachanoi), in the Peruvian Torch cactus (Echinopsis peruviana), and it is also found in a number of other members of the Cactaceae. It can be extracted from these sources. Mescaline was first isolated and identified in 1897 by the German Arthur Heffter and first synthesized in 1919 by Ernst Späth.

Contents

Usage and history

Mescaline powder
Mescaline powder

The use of extract from peyote in Native American religious ceremonies has been noted since the earliest European contact, notably by the Huichols in Mexico.

Dosage and effects

For the drug to take effect, disk-shaped buttons are cut from the roots, on the top of the cactus, and dried. It is chewed to produce its effect or soaked in water for an intoxicating drink. The effective human dosage is 0.3–0.5 grams, with the effects lasting for up to 12 hours. Users typically experience visual hallucinations and radically altered states of consciousness, often experienced as pleasurable and illuminating but occasionally as accompanied by feelings of anxiety or revulsion. It is not physically addictive.

Legal status

In the US it was made illegal in 1970 by the Comprehensive Drug Abuse Prevention and Control Act. It was prohibited internationally by the 1971 Convention on Psychotropic Substances[1] and is categorised as a Schedule I hallucinogen by the CSA.

Chemistry

A common synthetical approach starts from 3,4,5-trimethoxybenzaldehyde (PiHKAL entry).

Side effects

One or more of the following side effects may or may not accompany any individual experience with mescaline.

  • Open eye visuals
    Closed-eye visuals
    New thought processes
    Dream-like scenarios
    Euphoria
    Mystical experience
    Pupil dilation
    Sensations of warm and cold
    Temporary splitting/destruction of ego
    Dizziness
    Vomiting
    Tachycardia
    Diarrhea
    Headaches
    Anxiety
    Feeling of dying or genocide
    Fear of not being able to return to normal consciousness
    Hallucinogen persisting perception disorder (HPPD)
    Irrationality of the thought-process

Famous users

  • Jerry Garcia
    Aldous Huxley
    Carlos Santana
    Ernst Jünger [2]
    Leo Kenney [3]
    Henri Michaux [4]
    Jim Morrison
    Carlos Castaneda
    Hunter S. Thompson
    Allen Ginsberg
    Anton Malinsky
    Robert Del Naja
    Timothy Leary
    Christopher Mayhew, Labour MP and BBC television personality, who took Mescaline Hydrochloride in 1955 for an unbroadcast episode of Panorama [5]
    Jean-Paul Sartre
    Antonin Artaud
    Sébastien Branconnier
    Comedian Jim Breuer, in his stage act, talks about trying it once as a teenager, in a bit called "The Wizard".
    Stanisław Ignacy Witkiewicz, Polish writer, dramatist, photographer, philosopher and painter.
    Don Henley, Glenn Frey, Joe Walsh and Don Felder from The Eagles.
    Helen Reddy, singer, actress, and feminist activist
    Roland Deschain (AKA The Gunslinger), Although a fictional user - Roland's use of Mescaline is prevalent in the first book of the 'Dark Tower' cycle. Roland uses the drug in order to commune with a Demon in a stone circle, and protect the child Jake.
    In the film, The Royal Tenenbaums, the character Eli Cash admits to using Mescaline in a nonchalant manner. At the end of the film, it is possible he used Mescaline when he crashed his car into the Tenenbaums' house.
    In the film Domino (featuring Keira Knightley, Lucy Liu & Mickey Rourke), the bounty hunters have their coffee spiked with Mescaline as they attempt their escape.
    In the novel Fear and Loathing in Las Vegas and its film adaptation, Raoul Duke uses Mescaline.
    In the film The Matrix, one of Neo's friends Choi says that he uses Mescaline as it is "the only way to fly". But Yeshwanth disagrees to that statement.

See also

External links


Home | Up | Amphetamines | 2C-T-7 | 3,4-Methylenedioxyamphetamine | MDEA | Mescaline | Methylenedioxymethamphetamine | Methylphenidate

Drugs & Medication, made by MultiMedia | Free content and software

This guide is licensed under the GNU Free Documentation License. It uses material from the Wikipedia.


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